Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mthfrMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (660 aa)    
Predicted Functional Partners:
mtr
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.994
cth
Cystathionase (cystathionine gamma-lyase), like.
  
 0.986
tyms
Thymidylate synthetase.
    
 0.964
dmgdh
Dimethylglycine dehydrogenase.
  
 
 0.963
gldc
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
    
 0.960
SHMT2
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.959
ENSAPOP00000016870
SHMT domain-containing protein.
  
 
 0.959
shmt2
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.959
amt
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 
 0.952
LOC110952136
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b.
  
 0.944
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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