Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC110955867Protein kinase domain-containing protein. (430 aa)    
Predicted Functional Partners:
LOC110945637
Uncharacterized protein.
    
 0.922
grb2
Growth factor receptor-bound protein 2b.
    
 0.910
pgf
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.906
ENSAPOP00000005006
Phosphoinositide phospholipase C.
    
 0.906
LOC110964026
Phosphoinositide phospholipase C.
    
 0.906
LOC110955651
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.906
plcg1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.906
LOC110951398
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.904
gdnf
Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.
    
 0.904
fgf19
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.903
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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