STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC110965863Piezo-type mechanosensitive ion channel component 2a, tandem duplicate 2. (1711 aa)    
Predicted Functional Partners:
chek2
Checkpoint kinase 2.
    
 0.931
atr
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
   
 0.920
mcm4
DNA helicase; Belongs to the MCM family.
   
 0.852
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae).
    
 0.834
tipin
TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.
   
 
 0.832
wdhd1
WD repeat and HMG-box DNA binding protein 1.
   
 
 0.826
timeless
Timeless circadian clock.
    
 
 0.823
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.777
ENSAPOP00000010064
MCM_OB domain-containing protein.
   
 0.774
mcm2
DNA helicase; Belongs to the MCM family.
   
 0.774
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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