Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSAPOP00000003668Uncharacterized protein. (775 aa)    
Predicted Functional Partners:
ENSAPOP00000024610
Uncharacterized protein.
    
  0.698
ENSAPOP00000028898
Uncharacterized protein.
    
  0.698
nme9
NME/NM23 family member 8; Belongs to the NDK family.
    
 0.569
ENSAPOP00000006159
Uncharacterized protein.
    
  0.568
mysm1
Myb-like, SWIRM and MPN domains 1.
    
  0.552
ENSAPOP00000020317
GARS_A domain-containing protein.
     
  0.547
gart
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
     
  0.547
LOC110948645
BRCA1 associated RING domain 1.
    
 0.540
stk36
Serine/threonine kinase 36 (fused homolog, Drosophila).
    
  0.492
egr1
Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.
     
  0.490
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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