Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC110950007Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (407 aa)    
Predicted Functional Partners:
lamtor3
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.
   
 0.970
araf
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.969
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
   
 0.969
braf
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.969
map3k8
Mitogen-activated protein kinase kinase kinase 8.
    
 0.966
LOC110956697
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.958
map3k4
Mitogen-activated protein kinase kinase kinase 4.
    
 0.954
mapk1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.937
MAPK1
Mitogen-activated protein kinase.
   
 0.937
LOC110945879
Mitogen-activated protein kinase.
   
 0.937
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
Server load: low (24%) [HD]