Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPNS2Sphingolipid transporter 2. (515 aa)    
Predicted Functional Partners:
sgpl1
Sphingosine-1-phosphate lyase 1.
      
 0.863
kdsr
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.820
ENSAPOP00000013113
Uncharacterized protein.
     
 0.818
acer1
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.752
acer2
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.731
sgpp1
acidPPc domain-containing protein.
    
 0.720
LOC110958948
Si:ch211-212g7.6.
    
 0.720
smpd1
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
   
 0.716
ugcg
UDP-glucose ceramide glucosyltransferase.
     
 0.713
rtraf
RNA transcription, translation and transport factor.
    
 0.706
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
Server load: low (12%) [HD]