Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
man2b2Alpha-mannosidase. (1017 aa)    
Predicted Functional Partners:
man2c1
Mannosidase, alpha, class 2C, member 1.
     
 0.941
man2b1
Alpha-mannosidase.
     
 0.875
man2a2
Alpha-mannosidase.
     
 0.812
LOC110966229
Alpha-mannosidase.
     
 0.812
siae
Sialic acid acetylesterase.
    
 
 0.802
LOC110970049
Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase b.
   
 
 0.795
LOC110954575
Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a.
   
 
 0.795
gla
Alpha-galactosidase.
   
 
 0.781
naga
Alpha-galactosidase.
   
 
 0.781
NAAA
N-acylethanolamine acid amidase; Belongs to the acid ceramidase family.
    
 
 0.749
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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