Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ambra1Autophagy/beclin-1 regulator 1b. (1378 aa)    
Predicted Functional Partners:
becn1
Beclin 1, autophagy related.
    
 0.996
ddb1
Damage-specific DNA binding protein 1.
    
 0.984
LOC110950540
Unc-51 like autophagy activating kinase 1a.
   
 0.981
ulk2
Unc-51 like autophagy activating kinase 2.
   
 0.981
LOC110962333
Unc-51 like autophagy activating kinase 1.
   
 0.981
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.979
huwe1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
    
 0.977
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
   
 0.970
pink1
PTEN induced kinase 1.
    
 0.968
LOC110971589
DET1 and DDB1 associated 1.
    
 0.964
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
Server load: low (12%) [HD]