Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nrg4EGF-like domain-containing protein. (109 aa)    
Predicted Functional Partners:
erbb2
Receptor protein-tyrosine kinase.
    
 0.951
ENSAPOP00000006268
Recep_L_domain domain-containing protein.
    
 0.944
LOC110959808
Erb-b2 receptor tyrosine kinase 4.
    
 0.944
ENSAPOP00000025171
Uncharacterized protein.
    
 0.944
nrg2
Neuregulin 2a.
    
 0.936
nrg1
Neuregulin 1.
    
 0.936
LOC110970266
Uncharacterized protein.
    
 0.936
ENSAPOP00000011374
Receptor protein-tyrosine kinase.
    
 0.935
ENSAPOP00000012726
Recep_L_domain domain-containing protein.
    
 0.935
LOC110950702
Protein kinase domain-containing protein.
    
 0.935
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.