Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC110970708PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (496 aa)    
Predicted Functional Partners:
pdgfrb
Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.995
pdgfra
Platelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.988
flt3
Fms-related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.984
pdgfd
Platelet derived growth factor d; Belongs to the PDGF/VEGF growth factor family.
     
 0.953
pdgfc
Platelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family.
     
 0.953
vegfd
Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.
     
 0.947
flt1
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.944
LOC110954012
Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family.
    
 0.943
pdgfa
Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family.
    
 0.943
tie1
Tyrosine kinase with immunoglobulin-like and EGF-like domains 1.
    
 0.937
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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