Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSAPOP00000004084HECT domain-containing protein. (198 aa)    
Predicted Functional Partners:
rbbp5
Retinoblastoma binding protein 5.
    
 0.819
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.789
wdr6
WD repeat domain 6.
    
   0.785
dot1l
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
    
 0.690
setd2
SET domain containing 2, histone lysine methyltransferase.
   
 
 0.639
LOC110968432
SET binding protein 1.
   
 0.630
LOC110955211
Ash1 (absent, small, or homeotic)-like (Drosophila).
   
 0.630
ENSAPOP00000033255
Uncharacterized protein.
   
 0.630
LOC110953502
Uncharacterized protein.
   
 0.622
LOC110949372
Uncharacterized protein.
   
 0.622
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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