Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hic2Hypermethylated in cancer 2. (587 aa)    
Predicted Functional Partners:
sirt1
Deacetylase sirtuin-type domain-containing protein.
    
 
 0.887
LOC110964673
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.719
ube2i
Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.719
ENSAPOP00000024610
Uncharacterized protein.
    
  0.698
ENSAPOP00000028898
Uncharacterized protein.
    
  0.698
NUDCD1
NudC domain containing 1.
    
   0.689
LOC110960907
NudC domain containing 1.
    
   0.689
mta1
Metastasis associated 1.
    
 0.683
zbtb8a
Zinc finger and BTB domain containing 8A.
    
   0.678
LOC110961201
Protein inhibitor of activated STAT, 2.
    
  0.629
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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