Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC110964706Cyclin D2, b; Belongs to the cyclin family. (294 aa)    
Predicted Functional Partners:
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.984
rb1
Retinoblastoma 1.
    
 0.980
LOC110965132
Retinoblastoma-like 2 (p130).
    
 0.979
rbl1
Retinoblastoma-like 1 (p107).
    
 0.979
cdk4
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.976
LOC110954849
Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).
    
 0.976
cdk6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.976
LOC110950882
Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).
    
 0.970
LOC110953596
Cyclin-dependent kinase inhibitor 1D.
   
 0.960
cdkn1b
Cyclin-dependent kinase inhibitor 1Bb.
   
 0.960
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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