Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tmbim4Transmembrane BAX inhibitor motif containing 4; Belongs to the BI1 family. (237 aa)    
Predicted Functional Partners:
sigmar1
Sigma non-opioid intracellular receptor 1.
      
 0.681
psmb2
Proteasome subunit beta.
   
 
 0.661
rcn2
Reticulocalbin 2.
      
 0.660
llph
LLP homolog, long-term synaptic facilitation factor.
      
 0.660
chp1
Calcineurin-like EF-hand protein 1.
      
 0.633
krtcap2
Keratinocyte associated protein 2.
   
  
 0.611
tmem97
Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
      
 0.600
tmbim6
Testis enhanced gene transcript (BAX inhibitor 1); Belongs to the BI1 family.
   
  
 0.572
tmem147
Transmembrane protein 147.
   
  
 0.564
trim45
Tripartite motif containing 45.
    
 
 0.553
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.