Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSAPOP00000004347Sphingomyelin phosphodiesterase 3, neutral. (524 aa)    
Predicted Functional Partners:
ENSAPOP00000013113
Uncharacterized protein.
     
 0.983
smpd4
Sphingomyelin phosphodiesterase 4.
     
 0.982
smpd1
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
     
 0.961
ugcg
UDP-glucose ceramide glucosyltransferase.
     
 0.934
acer2
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.929
plpp1
Phospholipid phosphatase 1a.
     
 0.928
LOC110961486
acidPPc domain-containing protein.
     
 0.928
asah1
N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family.
     
 0.923
degs2
Delta(4)-desaturase, sphingolipid 2.
     
 0.910
LOC110969707
Neutral ceramidase.
     
 0.910
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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