Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mtpapMitochondrial poly(A) polymerase. (581 aa)    
Predicted Functional Partners:
calcoco2
SKICH domain-containing protein.
    
 
 0.958
grsf1
G-rich RNA sequence binding factor 1.
    
 0.914
hectd1
HECT domain containing 1.
   
   0.782
polr2g
Polymerase (RNA) II (DNA directed) polypeptide G-like.
    
  0.769
POLR2E
RNA polymerase II subunit E.
    
  0.762
polr2c
Polymerase (RNA) II (DNA directed) polypeptide C.
    
  0.762
polr2j
Polymerase (RNA) II (DNA directed) polypeptide J.
    
  0.762
polr2b
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.762
polr2h
DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
    
  0.762
polr2f
Polymerase (RNA) II (DNA directed) polypeptide F.
    
  0.762
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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