Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ankrd27Ankyrin repeat domain 27 (VPS9 domain). (1081 aa)    
Predicted Functional Partners:
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.965
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 
 0.899
rab21
RAB21, member RAS oncogene family.
    
 0.877
ubxn11
UBX domain protein 11.
    
 0.814
rabep1
Rabaptin, RAB GTPase binding effector protein 1.
    
 0.790
LOC110956699
Rabaptin, RAB GTPase binding effector protein 2.
    
 0.790
LOC110962300
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a.
    
   0.744
nfkbia
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b.
    
   0.744
rabgef1
Uncharacterized protein.
     
 0.737
LOC110960074
RAB guanine nucleotide exchange factor (GEF) 1, like.
     
 0.737
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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