Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC110958604RING-type domain-containing protein. (194 aa)    
Predicted Functional Partners:
LOC110956357
Poly [ADP-ribose] polymerase.
   
 
 0.925
ENSAPOP00000021603
Poly [ADP-ribose] polymerase.
   
 
 0.921
LOC110957121
Notch receptor 1b.
    
 0.894
LOC110954188
Notch receptor 1a.
    
 0.894
LOC110965747
Notch receptor 3.
    
  0.887
LOC110958453
Notch receptor 2.
    
  0.887
ENSAPOP00000004904
Uncharacterized protein.
   
 
 0.868
ENSAPOP00000007287
Macro domain-containing protein.
   
 
 0.868
ENSAPOP00000020975
Macro domain-containing protein.
   
 
 0.868
fam162a
Family with sequence similarity 162 member A.
   
 
 0.868
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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