Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
lig4DNA ligase. (908 aa)    
Predicted Functional Partners:
xrcc5
X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.
   
 0.997
xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6.
   
 0.996
dclre1c
DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae).
   
 0.993
prkdc
Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.
    
 0.991
APLF
Aprataxin and PNKP like factor.
    
 
 0.990
xrcc4
Uncharacterized protein.
    
 0.989
LOC110957050
X-ray repair complementing defective repair in Chinese hamster cells 4.
   
 0.984
rad52
RAD52 homolog, DNA repair protein.
    
 
 0.974
nhej1
Nonhomologous end-joining factor 1.
    
 0.969
paxx
PAXX non-homologous end joining factor.
    
 0.965
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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