Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC110951689TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (246 aa)    
Predicted Functional Partners:
LOC110948316
CD40 molecule, TNF receptor superfamily member 5.
    
 0.999
LOC110952318
Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.
   
 
 0.951
ENSAPOP00000011127
TNFR-Cys domain-containing protein.
    
 0.943
LOC110964690
TNFR-Cys domain-containing protein.
    
 0.940
ENSAPOP00000034133
Uncharacterized protein.
    
 0.940
LOC110945380
Death domain-containing protein.
     
 0.932
furin
Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family.
      
 0.885
tnfsf13b
TNF superfamily member 13b; Belongs to the tumor necrosis factor family.
     
 0.876
traf3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.870
LOC110962059
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.870
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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