Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dlx3Distal-less homeobox 3b. (280 aa)    
Predicted Functional Partners:
meis2
Meis homeobox 2a.
    
 
 0.857
LOC110963635
Meis homeobox 1 b.
    
 
 0.857
LOC110965248
Meis_PKNOX_N domain-containing protein.
    
 
 0.734
lef1
Lymphoid enhancer-binding factor 1.
    
 0.729
ENSAPOP00000008208
Forkhead box N1.
    
 
 0.709
foxi2
Forkhead box i1.
    
 
 0.698
LOC110950913
Keratin 5; Belongs to the intermediate filament family.
   
  
 0.693
tradd
Tnfrsf1a-associated via death domain.
      
 0.684
LOC110960464
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.682
bambi
BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.
   
  
 0.660
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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