Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC110963486Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)    
Predicted Functional Partners:
LOC110955917
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.907
PPP1CB
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.907
LOC110962016
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.907
LOC110956346
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
    
 0.895
LOC110957972
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
    
 0.895
camk2b
Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2.
    
 0.895
LOC110964357
Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2.
    
 0.895
LOC110958832
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
    
 0.895
LOC110948379
Protein kinase domain-containing protein.
    
  0.894
LOC110952258
Protein kinase domain-containing protein.
    
  0.894
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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