Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSAPOP00000005396Peptidase M12B domain-containing protein. (290 aa)    
Predicted Functional Partners:
AXL
AXL receptor tyrosine kinase.
    
 0.740
adam10
Uncharacterized protein.
     
 0.691
LOC110950365
ADAM metallopeptidase domain 10b.
     
 0.691
LOC110971065
ADAM metallopeptidase domain 17a.
     
 0.680
adam17
ADAM metallopeptidase domain 17b.
     
 0.680
LOC110970564
Uncharacterized protein.
    
  0.640
LOC110949988
C-mer proto-oncogene tyrosine kinase a.
    
  0.640
ENSAPOP00000031808
TYRO3 protein tyrosine kinase.
    
  0.640
sh3pxd2b
SH3 and PX domains 2B.
    
 0.560
sh3pxd2a
Uncharacterized protein.
    
 0.560
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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