Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC110962791Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily. (476 aa)    
Predicted Functional Partners:
LOC110971047
Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.
   
 0.989
LOC110969058
Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.
   
 0.989
LOC110956871
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
  
  
 
0.927
LOC110964146
Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily.
  
  
 
0.927
ssrp1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 0.919
dvl1
Dishevelled segment polarity protein 1a.
    
 0.919
dvl2
Dishevelled segment polarity protein 2.
    
 0.919
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 0.917
pcgf5
Polycomb group ring finger 5a.
    
 0.915
LOC110956182
Uncharacterized protein.
   
 0.907
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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