Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
bdh23-hydroxybutyrate dehydrogenase, type 2. (247 aa)    
Predicted Functional Partners:
LOC110963246
3-hydroxybutyrate dehydrogenase, type 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.911
oxct1
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 0.909
aacs
Acetoacetyl-CoA synthetase.
    
 0.882
hmgcl
3-hydroxy-3-methylglutaryl-CoA lyase.
  
 
 0.874
LOC110945198
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1.
  
 
 0.842
LOC110967482
3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic-like.
  
 
 0.842
LOC110964541
Hydroxysteroid (17-beta) dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.836
mcat
Malonyl CoA:ACP acyltransferase (mitochondrial).
  
 0.831
sord
Sorbitol dehydrogenase.
  
 
 0.821
oxsm
3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 0.821
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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