Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
KMT2ALysine methyltransferase 2A. (4562 aa)    
Predicted Functional Partners:
rbbp5
Retinoblastoma binding protein 5.
    
 0.987
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.982
wdr5
WD repeat domain 5.
   
 0.980
men1
Multiple endocrine neoplasia I.
    
 0.979
LOC110955211
Ash1 (absent, small, or homeotic)-like (Drosophila).
   
 0.969
dot1l
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
   
 0.946
PSIP1
PC4 and SFRS1 interacting protein 1.
    
 0.943
setd2
SET domain containing 2, histone lysine methyltransferase.
   
 
 0.913
LOC110948069
CREB binding protein a.
   
 0.909
crebbp
CREB binding protein b.
   
 0.909
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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