Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
wnk4WNK lysine deficient protein kinase 4b. (1500 aa)    
Predicted Functional Partners:
stk39
Serine threonine kinase 39.
    
 0.909
LOC110969471
Oxidative stress responsive kinase 1a.
    
 0.909
oxsr1
Oxidative stress responsive kinase 1b.
    
 0.909
trpv5
Transient receptor potential cation channel, subfamily V, member 6; Belongs to the transient receptor (TC 1.A.4) family.
    
 0.900
LOC110955255
Protein kinase domain-containing protein.
    
  0.849
med17
Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.810
LOC110969868
Protein kinase domain-containing protein.
    
 0.805
med14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.805
sgk2
Serum/glucocorticoid regulated kinase 2a; Belongs to the protein kinase superfamily.
    
 0.805
LOC110969757
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.805
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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