Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC110967544Formin homology 2 domain containing 3b. (1449 aa)    
Predicted Functional Partners:
rock2
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
 0.856
LOC110948042
Rho-associated, coiled-coil containing protein kinase 2b; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    
 0.830
LOC110965828
FH2 domain-containing protein.
     
  0.819
rock1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
 0.773
LOC110950482
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    
 0.519
ENSAPOP00000014451
Uncharacterized protein.
    
 0.519
ccdc151
Uncharacterized protein.
    
 0.519
cdc42bpb
CDC42 binding protein kinase beta (DMPK-like); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    
 0.519
cdc23
CDC23 (cell division cycle 23, yeast, homolog).
    
 
 0.474
ENSAPOP00000003936
Stabilin 2.
      
 0.414
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
Server load: low (10%) [HD]