STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSAPOP00000006400annotation not available (86 aa)    
Predicted Functional Partners:
rnf8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
   
 0.721
LOC110964394
RAN binding protein 2.
   
 0.710
rbpj
Recombination signal binding protein for immunoglobulin kappa J region.
   
 0.647
LOC110961546
Recombination signal binding protein for immunoglobulin kappa J region-like.
   
 0.647
LOC110954674
Recombination signal binding protein for immunoglobulin kappa J region a.
   
 0.647
zfand4
Zinc finger, AN1-type domain 4.
    
 0.642
pias4
Protein inhibitor of activated STAT, 4a.
    
  0.624
ENSAPOP00000003675
Ubiquitin-like domain-containing protein.
    
 0.621
LOC110967832
Diphthamide biosynthesis 3.
    
 
 0.605
rabgef1
Uncharacterized protein.
    
 0.603
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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