Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ing5Inhibitor of growth protein. (241 aa)    
Predicted Functional Partners:
meaf6
MYST/Esa1-associated factor 6.
   
 0.982
brpf1
Uncharacterized protein.
    
 0.954
LOC110962689
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.945
LOC110962671
Bromodomain and PHD finger containing, 3b.
    
 0.944
LOC110960662
Bromodomain and PHD finger containing, 3a.
    
 0.944
kat6a
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.933
JADE2
Jade family PHD finger 2.
    
 0.920
ENSAPOP00000024630
Uncharacterized protein.
    
 0.920
ENSAPOP00000016834
Jade family PHD finger 1.
    
 0.918
jade3
Jade family PHD finger 3.
    
 0.918
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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