Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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eif2aEukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (571 aa)    
Predicted Functional Partners:
EIF2AK4
Eukaryotic translation initiation factor 2 alpha kinase 4.
   
 
 0.945
eif2s1
Eukaryotic translation initiation factor 2, subunit 1 alpha b.
   
 
 0.928
eif3b
Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.
   
 
 0.914
xrn1
5'-3' exoribonuclease 1.
   
 
 0.914
eif2ak1
Eukaryotic translation initiation factor 2-alpha kinase 1.
   
 
 0.905
riok2
RIO kinase 2 (yeast).
   
   0.900
rps2
Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
   
  0.900
eif2ak3
Eukaryotic translation initiation factor 2-alpha kinase 3.
   
 
 0.895
zwilch
Zwilch kinetochore protein.
    
 
 0.889
ENSAPOP00000000342
Ribosomal_S3_C domain-containing protein.
   
  0.880
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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