STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brip1BRCA1 interacting protein C-terminal helicase 1. (1400 aa)    
Predicted Functional Partners:
brca1
Uncharacterized protein.
   
 0.993
mlh1
MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).
   
 0.992
topbp1
DNA topoisomerase II binding protein 1.
   
 0.992
slf1
SMC5-SMC6 complex localization factor 1.
  
 0.989
LOC110948645
BRCA1 associated RING domain 1.
  
 0.977
pms2
PMS1 homolog 2, mismatch repair system component.
   
 0.976
gtf2h1
General transcription factor IIH, polypeptide 1.
    
 0.972
LOC110959869
General transcription factor IIH subunit.
    
 0.972
ercc3
Excision repair cross-complementation group 3.
   
 0.972
mre11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
  
 0.972
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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