Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pigsPhosphatidylinositol glycan anchor biosynthesis, class S. (562 aa)    
Predicted Functional Partners:
gpaa1
Glycosylphosphatidylinositol anchor attachment 1.
   
 0.999
pigu
Phosphatidylinositol glycan anchor biosynthesis, class U.
   
 0.999
pigk
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
   
 0.999
pigt
Phosphatidylinositol glycan anchor biosynthesis, class T.
   
 0.999
ENSAPOP00000000919
PGRP domain-containing protein.
   
 0.969
LOC110967285
Peptidoglycan recognition protein 2.
   
 0.969
pgap1
GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi.
    
 0.942
pigg
Phosphatidylinositol glycan anchor biosynthesis class G.
   
 0.924
pigf
Phosphatidylinositol glycan anchor biosynthesis, class F.
     
 0.909
kdsr
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
  0.848
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.