| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC110962689 | atm | ENSAPOP00000027715 | ENSAPOP00000028362 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Non-specific serine/threonine protein kinase. | 0.996 |
| LOC110962689 | atr | ENSAPOP00000027715 | ENSAPOP00000008350 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | 0.984 |
| LOC110962689 | brca1 | ENSAPOP00000027715 | ENSAPOP00000023730 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Uncharacterized protein. | 0.978 |
| LOC110962689 | chek2 | ENSAPOP00000027715 | ENSAPOP00000004912 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Checkpoint kinase 2. | 0.992 |
| LOC110962689 | mdc1 | ENSAPOP00000027715 | ENSAPOP00000024241 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Uncharacterized protein. | 0.445 |
| LOC110962689 | paxip1 | ENSAPOP00000027715 | ENSAPOP00000031711 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | PAX interacting (with transcription-activation domain) protein 1. | 0.445 |
| LOC110962689 | topbp1 | ENSAPOP00000027715 | ENSAPOP00000021212 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | DNA topoisomerase II binding protein 1. | 0.876 |
| LOC110962689 | tp53bp1 | ENSAPOP00000027715 | ENSAPOP00000006674 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Tumor protein p53 binding protein, 1. | 0.973 |
| LOC110962689 | xrcc6 | ENSAPOP00000027715 | ENSAPOP00000010230 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | X-ray repair complementing defective repair in Chinese hamster cells 6. | 0.697 |
| atm | LOC110962689 | ENSAPOP00000028362 | ENSAPOP00000027715 | Non-specific serine/threonine protein kinase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.996 |
| atm | atr | ENSAPOP00000028362 | ENSAPOP00000008350 | Non-specific serine/threonine protein kinase. | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | 0.999 |
| atm | brca1 | ENSAPOP00000028362 | ENSAPOP00000023730 | Non-specific serine/threonine protein kinase. | Uncharacterized protein. | 0.993 |
| atm | chek2 | ENSAPOP00000028362 | ENSAPOP00000004912 | Non-specific serine/threonine protein kinase. | Checkpoint kinase 2. | 0.995 |
| atm | mdc1 | ENSAPOP00000028362 | ENSAPOP00000024241 | Non-specific serine/threonine protein kinase. | Uncharacterized protein. | 0.977 |
| atm | paxip1 | ENSAPOP00000028362 | ENSAPOP00000031711 | Non-specific serine/threonine protein kinase. | PAX interacting (with transcription-activation domain) protein 1. | 0.977 |
| atm | rnf168 | ENSAPOP00000028362 | ENSAPOP00000000359 | Non-specific serine/threonine protein kinase. | Uncharacterized protein. | 0.823 |
| atm | topbp1 | ENSAPOP00000028362 | ENSAPOP00000021212 | Non-specific serine/threonine protein kinase. | DNA topoisomerase II binding protein 1. | 0.919 |
| atm | tp53bp1 | ENSAPOP00000028362 | ENSAPOP00000006674 | Non-specific serine/threonine protein kinase. | Tumor protein p53 binding protein, 1. | 0.987 |
| atm | xrcc6 | ENSAPOP00000028362 | ENSAPOP00000010230 | Non-specific serine/threonine protein kinase. | X-ray repair complementing defective repair in Chinese hamster cells 6. | 0.979 |
| atr | LOC110962689 | ENSAPOP00000008350 | ENSAPOP00000027715 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.984 |