Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC110962211MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (462 aa)    
Predicted Functional Partners:
EIF4E
Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family.
    
 0.973
LOC110949064
Eukaryotic translation initiation factor 4ea; Belongs to the eukaryotic initiation factor 4E family.
    
 0.973
LOC110948527
Eukaryotic translation initiation factor 4E family member 1c; Belongs to the eukaryotic initiation factor 4E family.
    
 0.971
LOC110956697
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.961
mapk1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.956
MAPK1
Mitogen-activated protein kinase.
    
 0.956
LOC110945879
Mitogen-activated protein kinase.
    
 0.956
mapk7
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.919
LOC110965885
Activating transcription factor 4a.
     
 0.875
LOC110945652
Cyclic AMP-dependent transcription factor ATF-4-like.
     
 0.875
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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