Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC110953972KASH domain-containing protein. (2676 aa)    
Predicted Functional Partners:
ENSAPOP00000007033
Uncharacterized protein.
 
     0.914
sun1
Sad1 and UNC84 domain containing 1.
    
 0.898
ENSAPOP00000006937
Uncharacterized protein.
 
     0.729
trrap
Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.
    
 0.589
lmnb2
Lamin B2; Belongs to the intermediate filament family.
    
 0.560
LOC110969800
LEM domain-containing protein.
    
 
 0.559
lmna
Lamin A; Belongs to the intermediate filament family.
    
 0.558
LOC110968651
Uncharacterized protein; Belongs to the intermediate filament family.
    
 0.558
eny2
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]
    
 0.556
lmnb1
Lamin B1; Belongs to the intermediate filament family.
    
 0.543
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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