Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
etv1Ets variant 1. (543 aa)    
Predicted Functional Partners:
stk40
Serine/threonine kinase 40.
    
   0.974
det1
DET1 partner of COP1 E3 ubiquitin ligase.
    
 
 0.916
cop1
COP1 E3 ubiquitin ligase.
    
 
 0.877
ENSAPOP00000019155
Uncharacterized protein.
    
 
 0.877
ENSAPOP00000031312
RING-type domain-containing protein.
    
 
 0.877
LOC110954476
E1A binding protein p300 a.
    
 
 0.734
LOC110968598
E1A binding protein p300 b.
    
 
 0.734
ewsr1
EWS RNA-binding protein 1b.
    
 
 0.703
LOC110962689
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.694
srf
MADS-box domain-containing protein.
    
 0.671
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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