Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dcaf15DDB1 and CUL4 associated factor 15. (637 aa)    
Predicted Functional Partners:
LOC110971589
DET1 and DDB1 associated 1.
    
 0.801
DDA1
DET1 and DDB1 associated 1.
    
 0.801
ddb1
Damage-specific DNA binding protein 1.
    
 
 0.793
cul4b
Cullin 4B; Belongs to the cullin family.
    
 0.737
crbn
Cereblon.
     
 0.627
LOC110949440
Cullin 4A; Belongs to the cullin family.
    
 
 0.606
prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 
 0.603
DCAF1
DDB1 and CUL4 associated factor 1.
    
 0.576
LOC110970621
LisH domain-containing protein.
    
 0.576
dcaf4
WD repeat domain 21.
    
 0.568
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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