Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RASGEF1CRasGEF domain family member 1C. (489 aa)    
Predicted Functional Partners:
ENSAPOP00000030863
Intersectin 2a.
    
 0.770
LOC110950796
Intersectin 2b.
    
 0.770
lrguk
Leucine-rich repeats and guanylate kinase domain containing.
    
 0.752
LOC110951928
Uncharacterized protein.
    
  0.742
LOC110949257
Membrane associated guanylate kinase, WW and PDZ domain containing 3b.
    
  0.742
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.695
LOC110961531
CRK proto-oncogene, adaptor protein.
    
 0.695
LOC110970959
Uncharacterized protein.
    
 0.695
itsn1
Intersectin 1 (SH3 domain protein).
    
 0.679
LOC110957619
GRB2 related adaptor protein b.
    
 0.673
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
Server load: low (24%) [HD]