Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC110952819Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2140 aa)    
Predicted Functional Partners:
LOC110963487
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
   
 0.965
cacng1
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
   
 0.965
UNC79
Unc-79 homolog, NALCN channel complex subunit.
   
 0.937
LOC110955267
Calcium channel, voltage-dependent, alpha 2/delta subunit 2b.
   
 0.922
cacna2d1
Calcium voltage-gated channel auxiliary subunit alpha2delta 1.
   
 0.922
LOC110948569
Calcium channel, voltage-dependent, alpha 2/delta subunit 1a.
   
 0.922
cacna2d2
Calcium channel, voltage-dependent, alpha 2/delta subunit 2a.
   
 0.922
ENSAPOP00000025798
Protein kinase, cAMP-dependent, catalytic, beta a; Belongs to the protein kinase superfamily.
    
 0.887
cacna2d4
Calcium channel, voltage-dependent, alpha 2/delta subunit 4a.
   
 0.884
ENSAPOP00000030343
VWFA domain-containing protein.
   
 0.884
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
Server load: low (22%) [HD]