Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tll1Metalloendopeptidase. (915 aa)    
Predicted Functional Partners:
chrd
Chordin; Belongs to the chordin family.
   
 
 0.920
pcolce2
Procollagen C-endopeptidase enhancer 2b.
   
 0.727
LOC111571981
Procollagen C-endopeptidase enhancer a.
   
 0.727
scara5
Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways.
     
 0.609
LOC111579186
Collagen, type I, alpha 1b.
    
 0.601
LOC111588590
Collagen, type I, alpha 1a.
    
 0.601
LOC111573159
Sizzled.
    
 
 0.537
bmp4
Bone morphogenetic protein 4.
    
 
 0.536
LOC111570811
Bone morphogenetic protein 16.
    
 
 0.536
bmp2
Bone morphogenetic protein 2b.
    
 
 0.536
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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