Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
LOC111574955Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (188 aa)    
Predicted Functional Partners:
LOC111577019
Tyrosine-protein kinase.
    
 0.931
LOC111566214
Tyrosine-protein kinase.
    
 0.931
LOC111573260
Tyrosine-protein kinase.
    
 0.919
LOC111565178
Caveolae associated protein 1b.
   
 0.705
itgb3
Integrin beta; Belongs to the integrin beta chain family.
     
  0.687
LOC111567785
Integrin beta; Belongs to the integrin beta chain family.
     
  0.687
itgb6
Integrin beta; Belongs to the integrin beta chain family.
     
  0.687
itgb4
Integrin beta.
     
  0.687
LOC111584896
Integrin beta; Belongs to the integrin beta chain family.
     
  0.687
LOC111563530
Integrin beta; Belongs to the integrin beta chain family.
     
  0.687
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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