Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC111577195Pellino E3 ubiquitin protein ligase family member 3. (472 aa)    
Predicted Functional Partners:
irak4
Interleukin-1 receptor-associated kinase 4.
    
 0.876
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.863
irak1
Interleukin-1 receptor-associated kinase 1.
    
 0.843
LOC111572078
Ubiquitin-conjugating enzyme E2 variant 1.
    
 0.715
ube2n
Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.695
LOC111565827
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.695
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
    
 0.642
ENSAOCP00000025751
Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily.
    
 0.596
ube2v2
Ubiquitin-conjugating enzyme E2 variant 2.
    
 0.576
deaf1
DEAF1 transcription factor.
    
 
 0.571
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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