Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSAOCP00000001248HECT domain-containing protein. (66 aa)    
Predicted Functional Partners:
wdr6
WD repeat domain 6.
    
   0.626
rbbp5
Retinoblastoma binding protein 5.
    
 0.581
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.580
Dlgap5
Uncharacterized protein.
   
  
 0.502
cdca8
Cell division cycle associated 8.
   
 0.479
cdca2
PP1-binding domain-containing protein.
   
  
 0.474
mphosph8
M-phase phosphoprotein 8.
    
 0.473
eed
Embryonic ectoderm development.
   
 0.449
LOC111575440
Lysine (K)-specific demethylase 6A, like.
   
 0.448
kdm6b
Lysine (K)-specific demethylase 6B, a.
   
 0.448
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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