Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC111573137NUAK family, SNF1-like kinase, 1b. (663 aa)    
Predicted Functional Partners:
stk11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
    
 0.675
nt5dc3
5'-nucleotidase domain containing 3.
      
 0.590
LOC111577187
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.576
ENSAOCP00000014641
Uncharacterized protein.
    
 
 0.559
LOC111580923
Ubiquitin specific peptidase 9; Belongs to the peptidase C19 family.
    
 
 0.559
GUCY1A2
Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
      
 0.550
LOC111581134
AT rich interactive domain 1B (SWI1-like).
      
 0.544
fbxw11
F-box and WD repeat domain containing 11a.
    
   0.517
LOC111585088
Leiomodin 1b (smooth muscle).
   
  
 0.444
LOC111567881
SAMM50 sorting and assembly machinery component.
      
 0.439
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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