Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
grk4G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (564 aa)    
Predicted Functional Partners:
LOC111563032
Arrestin, beta 1.
    
 0.874
LOC111586232
Arrestin_C domain-containing protein.
    
 0.874
LOC111564191
Arrestin_C domain-containing protein.
    
 0.874
smo
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.863
LOC111571831
C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.
    
 0.701
LOC111571313
Chemokine (C-X-C motif) receptor 4a; Belongs to the G-protein coupled receptor 1 family.
    
 0.701
LOC111581085
Chemokine (C-X-C motif) receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.700
ENSAOCP00000019778
Chemokine (C-X-C motif) receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.700
ENSAOCP00000031321
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
    
 0.700
rcvrn
Recoverin a.
    
 0.698
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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