Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
httHuntingtin. (3065 aa)    
Predicted Functional Partners:
optn
Optineurin.
    
 
 0.967
sqstm1
Sequestosome 1.
    
 
 0.957
hypk
Huntingtin interacting protein K.
    
 
 0.936
prpf40a
PRP40 pre-mRNA processing factor 40 homolog A.
   
 0.933
setd2
SET domain containing 2, histone lysine methyltransferase.
    
 
 0.933
LOC111585205
Uncharacterized protein; Belongs to the synuclein family.
   
 
 0.919
LOC111573696
DSN1 component of MIS12 kinetochore complex.
   
 
 0.918
vcp
Valosin containing protein; Belongs to the AAA ATPase family.
   
 0.918
LOC111581806
Zgc:101679.
    
 
 0.918
LOC111577936
Zgc:136908; Belongs to the AAA ATPase family.
   
 0.918
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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