LOC111580106 protein (Amphiprion ocellaris) - STRING interaction network

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LOC111580106

Nuclear receptor binding SET domain protein 2. (1211 aa)

Predicted Functional Partners:

rrp8

0.800

LOC111577187

0.689

mre11

0.682

LOC111583696

0.678

rad50

0.661

rpl8

0.636

atm

0.620

mdc1

0.612

paxip1

0.612

bard1

0.597

Your Current Organism:

Amphiprion ocellaris

NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111577187	LOC111580106	ENSAOCP00000001385	ENSAOCP00000001394	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Nuclear receptor binding SET domain protein 2.	0.689
LOC111577187	LOC111583696	ENSAOCP00000001385	ENSAOCP00000004420	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Tumor protein p53 binding protein, 1.	0.986
LOC111577187	atm	ENSAOCP00000001385	ENSAOCP00000019655	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Non-specific serine/threonine protein kinase.	0.999
LOC111577187	bard1	ENSAOCP00000001385	ENSAOCP00000008446	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	BRCA1 associated RING domain 1.	0.987
LOC111577187	mdc1	ENSAOCP00000001385	ENSAOCP00000022597	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Uncharacterized protein.	0.472
LOC111577187	mre11	ENSAOCP00000001385	ENSAOCP00000032119	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.987
LOC111577187	paxip1	ENSAOCP00000001385	ENSAOCP00000030476	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	PAX interacting (with transcription-activation domain) protein 1.	0.472
LOC111577187	rad50	ENSAOCP00000001385	ENSAOCP00000012175	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	RAD50 homolog, double strand break repair protein.	0.870
LOC111580106	LOC111577187	ENSAOCP00000001394	ENSAOCP00000001385	Nuclear receptor binding SET domain protein 2.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.689
LOC111580106	LOC111583696	ENSAOCP00000001394	ENSAOCP00000004420	Nuclear receptor binding SET domain protein 2.	Tumor protein p53 binding protein, 1.	0.678
LOC111580106	atm	ENSAOCP00000001394	ENSAOCP00000019655	Nuclear receptor binding SET domain protein 2.	Non-specific serine/threonine protein kinase.	0.620
LOC111580106	bard1	ENSAOCP00000001394	ENSAOCP00000008446	Nuclear receptor binding SET domain protein 2.	BRCA1 associated RING domain 1.	0.597
LOC111580106	mdc1	ENSAOCP00000001394	ENSAOCP00000022597	Nuclear receptor binding SET domain protein 2.	Uncharacterized protein.	0.612
LOC111580106	mre11	ENSAOCP00000001394	ENSAOCP00000032119	Nuclear receptor binding SET domain protein 2.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.682
LOC111580106	paxip1	ENSAOCP00000001394	ENSAOCP00000030476	Nuclear receptor binding SET domain protein 2.	PAX interacting (with transcription-activation domain) protein 1.	0.612
LOC111580106	rad50	ENSAOCP00000001394	ENSAOCP00000012175	Nuclear receptor binding SET domain protein 2.	RAD50 homolog, double strand break repair protein.	0.661
LOC111580106	rpl8	ENSAOCP00000001394	ENSAOCP00000029227	Nuclear receptor binding SET domain protein 2.	Ribosomal protein L8.	0.636
LOC111580106	rrp8	ENSAOCP00000001394	ENSAOCP00000023000	Nuclear receptor binding SET domain protein 2.	Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.	0.800
LOC111583696	LOC111577187	ENSAOCP00000004420	ENSAOCP00000001385	Tumor protein p53 binding protein, 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.986
LOC111583696	LOC111580106	ENSAOCP00000004420	ENSAOCP00000001394	Tumor protein p53 binding protein, 1.	Nuclear receptor binding SET domain protein 2.	0.678