ptch1 protein (Amphiprion ocellaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

ptch1

Patched 1. (1570 aa)

Predicted Functional Partners:

smo

0.992

LOC111562874

0.980

LOC111577345

0.980

shh

0.980

LOC111582838

0.977

boc

0.970

cdon

0.970

LOC111580255

0.966

smurf1

0.960

SMURF2

0.960

Your Current Organism:

Amphiprion ocellaris

NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111562874	LOC111580255	ENSAOCP00000008687	ENSAOCP00000031893	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Growth arrest-specific 1a.	0.826
LOC111562874	boc	ENSAOCP00000008687	ENSAOCP00000005309	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	BOC cell adhesion associated, oncogene regulated.	0.920
LOC111562874	cdon	ENSAOCP00000008687	ENSAOCP00000017777	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Cell adhesion associated, oncogene regulated.	0.920
LOC111562874	ptch1	ENSAOCP00000008687	ENSAOCP00000001417	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Patched 1.	0.980
LOC111562874	smo	ENSAOCP00000008687	ENSAOCP00000019058	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.757
LOC111577345	LOC111580255	ENSAOCP00000015412	ENSAOCP00000031893	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Growth arrest-specific 1a.	0.820
LOC111577345	boc	ENSAOCP00000015412	ENSAOCP00000005309	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	BOC cell adhesion associated, oncogene regulated.	0.917
LOC111577345	cdon	ENSAOCP00000015412	ENSAOCP00000017777	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Cell adhesion associated, oncogene regulated.	0.917
LOC111577345	ptch1	ENSAOCP00000015412	ENSAOCP00000001417	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Patched 1.	0.980
LOC111577345	smo	ENSAOCP00000015412	ENSAOCP00000019058	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.682
LOC111580255	LOC111562874	ENSAOCP00000031893	ENSAOCP00000008687	Growth arrest-specific 1a.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.826
LOC111580255	LOC111577345	ENSAOCP00000031893	ENSAOCP00000015412	Growth arrest-specific 1a.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.820
LOC111580255	LOC111582838	ENSAOCP00000031893	ENSAOCP00000028811	Growth arrest-specific 1a.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.826
LOC111580255	boc	ENSAOCP00000031893	ENSAOCP00000005309	Growth arrest-specific 1a.	BOC cell adhesion associated, oncogene regulated.	0.939
LOC111580255	cdon	ENSAOCP00000031893	ENSAOCP00000017777	Growth arrest-specific 1a.	Cell adhesion associated, oncogene regulated.	0.939
LOC111580255	ptch1	ENSAOCP00000031893	ENSAOCP00000001417	Growth arrest-specific 1a.	Patched 1.	0.966
LOC111580255	shh	ENSAOCP00000031893	ENSAOCP00000021381	Growth arrest-specific 1a.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.826
LOC111580255	smo	ENSAOCP00000031893	ENSAOCP00000019058	Growth arrest-specific 1a.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.589
LOC111582838	LOC111580255	ENSAOCP00000028811	ENSAOCP00000031893	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Growth arrest-specific 1a.	0.826
LOC111582838	boc	ENSAOCP00000028811	ENSAOCP00000005309	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	BOC cell adhesion associated, oncogene regulated.	0.917