Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fam171a2Family with sequence similarity 171 member A2b. (829 aa)    
Predicted Functional Partners:
LOC111578081
Carnitine palmitoyltransferase 1Ab (liver); Belongs to the carnitine/choline acetyltransferase family.
      
 0.705
LOC111579406
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
      
 0.616
LOC111583694
Uncharacterized protein.
      
 0.613
LOC111583220
Choline kinase beta.
      
 0.598
dnaaf3
Dynein, axonemal, assembly factor 3 like.
      
 0.594
LOC111584601
Uncharacterized protein; Belongs to the carnitine/choline acetyltransferase family.
      
 0.586
tmem208
Transmembrane protein 208.
      
 0.554
Meioc
Uncharacterized protein.
      
 0.543
kdm6b
Lysine (K)-specific demethylase 6B, a.
      
 0.514
tmem186
Transmembrane protein 186.
      
 0.509
Your Current Organism:
Amphiprion ocellaris
NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish
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